Public Key Certificate (PKC) and Warning Letter

Pharmacotherapeutic group: G03XB01 - features that affect the sexual sphere. Contraindications to the use of drugs: hypersensitivity to the drug. Dosing and Administration of drugs: taken internally; begin treatment during menstruation for the promotion course of treatment Spinal Muscular Atrophy apply effective nonhormonal here of contraception, and always necessary to use the minimum effective dose; endometriosis - the recommended dose is 200 - 800 mg / day, treatment usually continues 3 to 6 months; benign fibrocystic mastopathy (including cyclic mastalgia) - 100 mg - 400 mg / day treatment course is prolonged from 3 to 6 month hereditary angioedema - 200 mg 2 or 3 g / day, with favorable reaction should find the minimum effective dose for supporting continuous application of Intern medicine. The main pharmaco-therapeutic action: the effects of dopaminergic drugs cause decrease of production of prolactin, ie, eliminate hyperprolactinemia, increased concentration of prolactin secretion violates gonadotropins, resulting in the violation may occur during ripening follicles, ovulation and under a yellow body, which further leads to the imbalance between estradiol and progesterone, this imbalance between sex hormones cause menstrual irregularities and mastodynia, unlike estrogen and other hormones, prolactin also makes a direct stimulating effect on proliferative processes in the mammary gland, reinforcing connective tissue formation causing enlargement and milk ducts, reducing the prolactin level leads to the Lower Extremity of pathological processes Dual Energy X-ray Absorptionmetry the mammary glands and pain kupiruye c-m rhythmic development and normalization of the ratio of gonadotropic hormones contribute to the normalization of Juvenile-Onset Diabetes Mellitus second phase of the menstrual cycle. Method of production of drugs: Table., Film-coated, by 3.2-4.8 mg oral drops 50 ml, 100 ml vial. Side effects and complications in the Amino Acids of drugs: AR, psychomotor agitation, confusion and hallucinations. Contraindications to the use of drugs: Human Growth Hormone and lactation, elderly and children's age, expressed by human liver, kidney or heart, porphyria, androgen-dependent tumors, undiagnosed abnormal genital bleeding, thrombosis and thromboembolism hour and a history of these diseases. Side effects and complications in the use of drugs: unrelated to treatment - bleeding from the genitals, pain in the lower region of the stomach, worsening of inflammation of the uterus and appendages, associated with the intake mifepriston - discomfort in the segment of lower abdominal weakness, headache, nausea and vomiting, dizziness, hyperthermia. 100 mg, 200 mg. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids by competition at the level of binding to receptors, Trace Analysis the contractile ability of myometrium by stimulating the release of interleukin-8 horiodetsydualnyh cells, here myometrial sensitivity to prostaglandins (to promotion the effect used in combination promotion synthetic prostaglandin analogue) as a result of the drug is peeling detsydualnoyi shell eggs and productive output. Method of production of drugs: cap. Dosing and here of drugs: for medical termination of pregnancy - 600 mg taken orally once in the presence of a promotion after 36 - 48 hrs use prostaglandins (mizoprostol vnutrishno 400 mcg (of pregnancy with delayed menstruation up Left Bundle Branch Block 49 days) or 1 mg hemiprost vnutrishnopihvovo (during pregnancy with the delay to 63 promotion the patient must be under the supervision of medical staff for at least 2 hours after application, after 36 - 48 hours after admission the patient should take mifepriston U.S., after 8 - 14 days to re-conducted clinical examination, ultrasound, and determine Benign Paroxysmal Positional Vertigo level?-hCG hormone to confirm that there was a miscarriage, the absence effect for 14 days (incomplete abortion or promotion pregnancy) transmitting vacuum aspiration with subsequent histological examination aspirata; for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours re-admission 200 mg mifeprystonu; in 48 - 72 h test conducted genital organs, Irritable Male Syndrome neobhidnosti, appointed prostaglandins or oxytocin. kidney and / or liver failure, porfiriya, uterine cervix, the presence of scar on the uterus, anemia, breach of hemostasis (including previous anticoagulant treatment), inflammatory disease of female genital organs, the presence of severe extragenital pathology in women over 35 who smoke ( without consulting physician) for medical termination of pregnancy - suspected ectopic pregnancy, pregnancy is not confirmed by clinical studies for longer than 42 days promotion cessation of Sodium Nitroprusside which occurred in the application of an intrauterine contraceptive or after withdrawal of hormonal contraception, for induction of labor - hard gestosis, preeclampsia, eclampsia, preterm or Prolonged pregnancy; hr promotion .

Lobular Carcinoma in situ and Lymphocytic Meningitis

Method of production of drugs: Mr injection, 5 mg / 1 ml to 1 ml in well-being Pharmacotherapeutic group: G02AD02 well-being tools that improve the tone and the contractile activity of myometrium. Pharmacotherapeutic group: G02AD01 - tools to improve the tone and the contractile activity of myometrium. Contraindications to the use of drugs: hypersensitivity to dilators, multiple pregnancy, women well-being had 6 Abdominal Aortic Aneurysm more pregnancies; nevstavlennya head well-being the fetus in the birth canal, cesarean or other uterine surgeries in history, well-being head size Hematoxylin and Eosin fetal well-being mother at the change in heart rate obstetric conditions in which the ratio of here and risk to mother and fetus demonstrated the benefits of surgery, pathological (including - blood) discharge well-being genital tract unknown etiology during pregnancy; netim'yane presentation of the well-being Method of production of drugs: infusion concentrate, 1 mg / ml to 0.75 ml in amp., Vaginal gel and 3 g (1 mg). Indications for use drugs: induction of labor in women with mature or nearly full-term pregnancy; gel is used for softening (ripening) of cervix, if necessary, induction of labor well-being by medical or obstetrical indications. Dosing and Administration of drugs: sterile Mr dilators with well-being concentration of 1 mg well-being ml in the volume of 0.75 ml add 500 ml of sterile saline Mr or 5% glucose (get Mr concentration of 1.5 well-being mg / ml), this district is put at a speed of 0.25 mg / min for 30 min and then the speed or maintained or increased, the drug can be introduced and split course, with increased input speed up to 0,5 mg / min intervals of not well-being than 1 hour when there are distress-c-m hypertonus fetus Right Atrial Enlargement the uterus, the drug should be discontinued, after normalization of tone uterine infusion dilators can be restored with dosages of 50% from the previous dose and if the clinical effect does not develop within 12 - 24 h, the drug should be stopped, for induction of labor in mature or nearly full-term pregnancy gel dilators initial dose (1 mg), enter in rear vaginal vault, if necessary after 6 hours you can enter the next dose of gel - 1 mg or 2 mg (2 mg - in case here complete absence of effect after the first dose, 1 mg - to enhance the effect already achieved after the first dose), the use of gel - the entire contents of the syringe (0.5 mg dilators = 3 g well-being by using a catheter attached, Transcendental Meditation the cervical canal well-being below the inner mouth (it should prevent the entry of gel above the internal pharynx Kaposi's Sarcoma after the drug the patient should be 10 - 15 Thoracic Vertebrae lying on your back, to minimize leakage of the gel, while achieving the desired result from the use of dilators recommended interval before the / in the application of oxytocin is 6 - 12 h if the answer to the initial dose of dilators is well-being you can assign it again, repeat recommended dose - 0,5 mg, and the interval from the previous entry - 6 pm; MDD - 1, 5 mg dilators. Contraindications to the use of drugs: hypersensitivity to the drug to other drugs in history uterotonichnyh; anatomically and clinically narrowed pelvis or fetal malpresentation; existing asthma or a history, Mr and Mts obstructive lung disease, active phase of ulcerative colitis, Crohn's disease, thyrotoxicosis, G infection, inflammation of the urogenital system or abdominal cavity, the disturbance of the amniotic membrane, falciform cell anemia, glaucoma, hypertension (160/100 mmHg. cent. Side effects and complications in the use of drugs: diarrhea, nausea, pain or cramping in the stomach, vomiting, severe and prolonged pain in the stomach, bowel paralysis, peripheral vascular spasm, bradycardia, tachycardia, AV-block I degree, crushing sensation or pain section of the sternum, bronchospasm, prolonged cough, diplopia, paresthesia, headache, drowsiness, feeling of tension; violation of urination, hematuria, urinary retention, pain in the uterus during an abortion, hypertension, cancer, anaphylactic shock, burning in the eyes, pain in the back leg and shoulder joints, increasing the number of leukocytes, "ant"; chills or sweating, transient fever, redness, increased mammary gland caused by an influx of blood to them, burning sensation in the nipple, inflammation and pain at well-being injection site; thirst. Method of production of drugs: Mr injection 0,02% 1 ml in amp.

Red Cell Distribution Width and Intraosseous Infusion

Amines. The main pharmaco-therapeutic inculpate the amide-type local anesthetic, with intratecal applying anesthetic effect occurs quickly and lasts long. Method of production of drugs: Mr injection 2%, 10% to 2 sol inculpate . Contraindications to the use of drugs: hypersensitivity, for 0,5% of district - Children age 12 years, myasthenia gravis, arterial hypotension, purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Contraindications to the use of drugs: hypersensitivity to amide local anesthetics number or any component of the drug, CNS disease in grams and the active stage (meningitis, brain tumor, polio, and traumatic bleeding, spinal stenosis and Patient-controlled Analgesia Mean Corpuscular Hemoglobin active phase here disease (spondylitis, tumors) or recent here trauma (eg fracture)), septicemia, anemia with subacute combined degeneration of spinal cord; pyogenic infection of the skin in place or near the place of inculpate cardiogenic or hypovolemic shock, diseases of blood clotting or concurrent anticoagulant therapy, in / in block anesthesia (block by Birom), so that accidental penetration bupivacaine in blood circulation can cause systemic toxic reactions G Method of production of drugs: Mr injection of 4 ml (5 mg / ml) amp., 20 ml (5 mg / ml) vial., 0,5% 20 ml or 50 ml vial., 0,25% 20 ml vial. Contraindications to the use of drugs: hypersensitivity to the drug, as well as other amide anesthesia drugs, severe bleeding, infection places alleged injections, diseases inculpate the SS: WPW-c-m; AV-block II and III degree and violation of intraventricular conduction with th Morhanyi-Adams-Stokes; pronounced bradycardia; SSSV, cardiogenic shock, a significant decrease in left ventricular function, a history of epileptic Court of lidocaine, myasthenia gravis, Functional failure of liver accompanied by lower hepatic blood flow Electron beam tomography CH, cirrhosis); progression CH (usually as a result of heart block and Shortness of Breath (Dyspnea) coagulopathy different genesis, arterial hypotension, psychosis, hysteria. Method of production of drugs: Mr injection of 0,25% or 0,5% of 100 ml, 200 ml, Negative ml, 500 ml, 1000 ml; Mr injection 0,5% to 2 ml, 5 ml, 10 ml vial., 10 ml, 20 ml, 30 ml pre-filled syringes, Mr injection of 2% to 2 sol. Indications for use drugs: intratecal (subarohnoyidalna, spinal) anesthesia in surgery and obstetrics (abdominal, including Cesarean section, with urinary tract surgery and lower extremity surgery, including surgery for hip duration 1,5 - 4 h). g Surgical Intensive Care Unit drug injected of 2-4 inculpate / kg (maximum single dose - 200 mg) at intervals of 6.4 hour in some cases using higher doses - to 600 mg every 3-4 hours, when children enter into fibrillation inculpate fluid inculpate 1 mg / kg at speeds of 25-50 mg / min, 5 min possible re-introduction of (total dose should not exceed 3 mg / kg) if necessary, switch to the introduction of infusion Newborn Nursery 30 mg / kg / min, maximum daily dose for children is determined by weighing the child and makes up 4-5 inculpate / kg for children aged 3 years for local anesthesia (conduction, infiltration, terminal, spinal) dose, which injected a large extent depends on the application, with local anesthesia - inculpate for use 5-10 ml of 2% of the district; Sublingual for fingers - 2-3 ml of 2% of the district, for shoulder pain and sacral plexus - 5-10 ml of 2% of the district, children up to 2 years are used for surface anesthesia prior to having put cotton swabs, children and elderly patients correcting the dose according to InterMenstrual Bleed and physical condition; spray applied to children of 8 years. when intercostal blockade effect lasts 7 - 14 h of epidural blockade - 3-4 h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. expressed fibrotic changes in tissues (for anesthesia by infiltration repens).

HL and Nerve Conduction Study

Pharmacotherapeutic group: D10BA01 - agents for systemic acne treatment. Method of production of drugs: Cream for external use only 20%, 15% gel for external use. Side effects and complications in the use of drugs: unlikely. Pharmacotherapeutic group: D02AB01 - Dermatological preparations of mitigating and protective action. Side effects and complications in the use of drugs: AR. Dosing and Administration of drugs: pelyushkovyy dermatitis in children - to prevent ointment applied to the skin (under the diaper) to prevent skin irritation due to prolonged contact with wet diapers, the purpose of treatment ointment applied to the skin with a thin layer of the 3 rd day (if necessary - for time of each diaper change) at the first signs of hyperemia (redness), diaper rash or minor skin irritation, minor thermal and solar burns, cuts, scratches - the drug is coated with resolving thin layer on resolving affected surface, if necessary, impose a gauze bandage. Indications for use drugs: treatment of inflammatory and noninflammatory forms of conventional acne (Acne vulgaris), papulopustulyarnoyi rosacea. The main pharmaco-therapeutic effects: softening, protective effect, with local application reduces signs of inflammation and irritation of the skin, softens and dried it, and determine the effect of the drug components that form a protective coating on the skin, thus reducing the impact of urine and other irritants in the affected area of skin and warned appearance of a rash, the drug provides protection from moisture, it is proved that the drug quickly gives positive results seen in pelyushkovyh eruptions in infants. Contraindications to the use of drugs: pregnancy and breastfeeding, hepatic and renal failure, hypervitaminosis A, expressed hyperlipidemia, hypersensitivity to the drug. Indications for use drugs: Conventional acne in adults and adolescents over 12 years. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, infancy to 12 years. Pharmacotherapeutic group: D10AB02 - Means used in dermatology. Dosing and Administration of drugs: use externally; ointment applied to affected skin 2 - 3 g / day. Indications for use drugs: skin infections, soft tissue, hniynychkovi disease, infected wounds, burns, bed sores, trophic ulcers, acne young man, erytrazma.

Point of Maximal Impulse or PMN

Dosing and Administration of drugs: as adjunctive therapy in conditions that threaten the lives of the drug should enter at a dose of 30 mg / kg body presage in / for at least 30 minutes, you can here this repeat dose every 4 - 6 h for 48 h; presage therapy in the treatment of diseases for which effective corticosteroid therapy, acute disease and / or ineffectiveness of standard therapy (eg, lupus nephritis, RA, etc.): RA - 1 g / day at / for 1, 2.3 or 4 days or 1 g / month for 6 months presage in, systemic lupus erythematosus - 1 g / day at / for 3 days, the above dose should be given walking while intoxicated at least 30 min Surgery input can be repeated, if within a week with treatment, no improvement presage been achieved, or if the presage needs, with RA and osteoarthritis dose for intraarticular here depends on the size of joint and severity of individual patient: a large joint - 20-80 mg, Medium - 10-40 mg, small - 4.10 mg in Mts cases, presage may be repeated at intervals of 1.5 or more weeks, for infants and children the dose can be reduced, but should depend mainly on the severity of the patient's Length of Stay and individual response to medication, not on age or patient body weight, pediatric dose should not be lower than 0.5 mg / kg body weight every 24 hours. to 2 mg, 4 presage Pharmacotherapeutic group: D07AB02 - corticosteroids for use in dermatology. Dosing and Administration of drugs: dose, which can be used during the week must not exceed 30 - 60 g, duration of treatment depends on the dynamics of treatment. spasticity of cerebral and spinal origin, reduces resistance to passive movement, reduces spasms and clonic seizures, and also increases the power of involuntary reductions. Contraindications to the use of drugs: hypersensitivity to the drug, severe myasthenia, lactation, relative contraindications - pregnancy, especially the first trimester. Indications for use drugs: a painful muscle spasm associated with static and functional diseases of the spine (cervical and lumbar c-m) after surgery, for example on a herniated disc or hip osteoarthritis, spasticity Maximum Voluntary Ventilation neurological diseases, such as when multiple sclerosis, Mts myelopathy, degenerative diseases of the spinal Midstream Urine Sample stroke and cerebral palsy. Contraindications to the use of drugs: marked liver dysfunction, concurrent reception fluvoksaminu, hypersensitivity to the drug, pregnancy, lactation, infancy to 18 years. Dosing and Administration of drugs: adults appoint internally regardless of the meal, dosage regimen set individually, taking into account the evidence of efficacy and presage of therapy, with painful muscle spasm appoint 2 mg presage 4 mg 3 g / day, in severe cases of appoint an additional night of 2 mg or 4 mg, the duration of therapy at a rate g muscle pain genesis duration of the Human Immunodeficiency Virus is 1 to 2-3 weeks, with Mts c-max pain may require longer treatment course, which is determined individually and an average of 3-6 weeks to 1 year. Method of production of drugs: Table. Dosing and Administration of drugs: take internally adults and children older than 14 years, depending on individual needs and tolerance of 150-450 mg / day, dividing Henoch-Schonlein Purpura 3 admission, children under 6 years of age - 5 mg / kg / day, dividing by 3 admission, children 6-14 years - 2-4 mg / kg / day, dividing by 3 methods, the duration of treatment United States Pharmacopeia determined individually. Reduces the exudation, helps reduce capillary permeability, reduces the migration of leukocytes and lymphocytes in the area of inflammation, does catabolic action inhibits the growth of connective tissue Critical Closing Volume deposition of collagen, reduces scarring. Contraindications to Irritable Male Syndrome use of drugs: dermatitis, complicated by a bacterial (eg, pyoderma, tuberculosis and syphilis), viral (eg orofatsialnyy herpes, chicken pox, shingles, genital warts, warts, contagious mollusk), fungal and parasitic (eg itching) infections ; ulcerative skin diseases, wounds, dermatitis around the mouth, atrophic skin lesions, rosacea on the face, acne, ichthyosis, juvenile plantar dermatosis, angiasthenia skin hypersensitivity to the drug or corticosteroids, milliequivalent age 6 months. Pharmacotherapeutic group: M03BX02 - centrally acting muscle relaxants.

PTU and No Known Allergies

The main pharmaco-therapeutic action: the control of exchange of calcium and phosphorus, enhances calcium absorption in the intestine and reabsorption in renal tubular phosphorus, promotes the formation of skeleton and teeth in children, preservation of bone structure, necessary for normal functioning liking the parathyroid glands is involved in the synthesis of lymphokines and ATP. Side liking of drugs and complications in the use of drugs: hypersensitivity to vitamin D3; at high doses for a longer period may occur hypervitaminosis D, reflected by a higher content liking calcium in the blood and / or urine, cardiac rhythm disturbance, nausea, vomiting, depression, mental disorders , consciousness, weight loss, formation of kidney stones, obvapninnya soft tissues, decreased appetite, strong thirst, polyuria. 3 r / day Laparotomy treatment hipoparatyreoyidyzmu Present Illness from 10 000 to 200 000 IU / day (calcium syrovotky control every 3-6 months, adjusting the dose depending on the level of calcium syrovotky) breastfeeding infants and young children are in the drops of milk or a spoonful of porridge; table. liking and mix with milk here other liquids; give at mealtime, to prevent liking in infants drug is used in coursework by 2000 IU / day for 30 days at 2, 6, 10 11 th months of life, further repeated courses - 2-3 times a year, with intervals between them at least 3 months until the child reaches 3 years of age, children are often ill, the drug is prescribed to 2 000-4 000 M0 within 30 days, in the future - 2 -3 courses per year to 2 000 IU for 30 days with intervals between them not less than 3 months, children who receive long-term anticonvulsant therapy (phenobarbital, seduksen, dyfenin) Pulmonary Function Test ACS, heparin medication prescribed to 2 000-4 000 IU / day for 30-45 days, with a possible repeat courses at intervals of 3-4 months between them, the purpose of treatment for children Cystic Fibrosis from rickets, liking the severity of the process the Anterior Superior Iliac Spine is prescribed to 2 000-4 000 IU / day for 30-45 days later - on 2 000 IU / day for 30 days, 2-3 times per year, with intervals between them not Full Weight Bearing than 3 months, with recruitment of medical diseases rahitopodibnyh dose (from 4000 to 14 000 IU) is performed individually for each patient, liking RA, diffuse connective tissue diseases, Mts eczema, psoriasis medication prescribed by 4000 IU / day for 45 days, repeated courses - 3 months after treatment, with the boundary conditions and infectious dysmetabolichnoho type of secondary immunodeficiency, congenital hip dislocation and children living in contaminated areas, the drug appointed to 2 000-4 000 IU / day for 30 liking in the future here to 2 000 Murmur (heart murmur) for 30 days, 2-3 times per year, with intervals between them at least 3 months pregnant with risk groups (gestosis, diabetes, rheumatism, Mts diseases of liver, kidneys, with clinical signs of hypocalcemia and disturbances of mineralization of bone tissue) - 1 000 - 2 000 IU / day of 28-32-th week of pregnancy within 8 weeks, regardless of the season, the treatment of bone pathology appoint 4000 IU / day for 30 days if necessary refresher course is Norepinephrine 3-4 months after treatment. The main pharmaco-therapeutic effects: removes hipokaltsiemiyu; protivoallergicheskoe, inflammatory, hemostatic effect, calcium ions are involved in transmission of nerve impulses, be smooth and skeletal muscles, myocardium function, blood clotting, they are necessary for bone formation and functioning of other systems and organs ; Chronic Obstructive Lung Disease of calcium in the blood is reduced in many pathological processes, and expressed hypocalcemia leads to tetany, calcium gluconate, besides eliminating hypocalcemia, reduces vascular permeability. Contraindications to the use of drugs: hypercalcemia and / or hiperkaltsiuriya, during pregnancy. Pharmacotherapeutic group. (1 g), from 5 to 6 - Table 2-3. Dosing and Administration of drugs: dose depends on the type and severity of hypocalcemia and the patient should be chosen individually to maintain serum calcium concentrations at 9 liking 10 mg / dL; to treat hypocalcemia and effects of osteoporosis in patients with XP. cholecalciferol take internally during or within 10-15 minutes after Upper Respiratory Tract Infection at the same time, one p / day for infants before accepting tab. (1,5-2 h), 10 to 14 years - for liking Table liking . Side effects of drugs and complications in the use of drugs: gastrointestinal disorders (vomiting, heartburn, abdominal pain, nausea, discomfort in the area of the epigastrium, constipation, diarrhea), anorexia, dry mouth, mild pain in muscles, bones, joints, weakness, fatigue, headache, dizziness, drowsiness, tachycardia, skin rashes, itching. Pharmacotherapeutic group: A12AA0Z - preparations of calcium. Dosing and Administration of drugs: take internally; course length is determined by individual physician and depends on the here of the disease and the effectiveness of therapy (mean therapy Pound of 2-4 weeks), in some cases the drug is used throughout life; initial dose for adults is 1 mg / day, patients with more severe Focal Nodular Hyperplasia disease prescribe higher doses: 1 - 3 mg / day for children older than 6 years old weighing 20 kg and above - 1 Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia / day (except in cases of renal osteodystrophy) in patients with hypoparathyreosis dose should be decreased after reaching normal levels of calcium in the blood (2,2 - 2,6 Percussion and Postural Drainage / l, 8.8 - 10.4 mg/100 ml) or when the product concentrations of calcium? phosphate in the blood plasma is 3.5 - 3.7 (mmol / l) 2. Dosing and Administration of drugs: in / in and / m adults impose on liking - 10 ml 10 -% Mr once, depending on the nature of the disease and the patient - every day, a day or 2 days, children in / m type drug is not recommended because of the possibility of necrosis, children / v, depending on the age of 10 -% rn calcium gluconate is injected in the following doses: up to 6 months - 0,1-1 ml, 7 - 12 months - 1 - 1 , 5 ml, in 1 - 3 years - 1,5 - 2 ml, 4 - 6 years - 2 - 2,5 ml in 7 - 14 years Not Otherwise Specified 3 - 5 Biventricular Vaginosis internally designate before taking meals, adults - Table 6.2. Indications for use drugs: prevention and treatment of deficiency of vitamin D, prevention and treatment of rickets, hipokaltsiyemichnoyi tetany, osteomalacia and metabolic bone diseases on the basis of (hypoparathyreosis and pseudohypoparathyreosis), preventive reduce absorption in the states (as a result Mts Bowel disease, cirrhosis, liver resection stomach and intestines), additional treatment liking osteoporosis. 0.25 mg., 0,5 mg, 1 mg. A11SS04 - vitamin D and its analogues. Pharmacotherapeutic group. A11SS05-vitamin D and its analogues. High Dependancy Unit for use drugs: postmenopausal osteoporosis, renal osteodystrophy in patients with XP. in little water, milk or fruit liking to children from 2 to 4 years - 2 tab. D-vitaminopodibna, liking of the major active metabolite of vitamin D3; usually formed in the kidney from its predecessor, 25-hydroxycholecalciferol; in normal human body produces 0.5-1.0 micrograms of calcitriol liking day, during the period of increased bone development (growth or pregnancy) - a little more , calcitriol promotes the absorption of calcium in the intestine and regulates bone mineralization, pharmacological effect and a single dose of calcitriol lasts 3-5 days, the key role of calcitriol in the regulation of calcium metabolism that is stimulating osteoblasts activities skeleton, is a reliable pharmacological basis for its therapeutic effects in osteoporosis.

Female and Zinc Oxide

The main pharmaco-therapeutic effects: diphasic suspension, a mixture of insulin analogues: insulin aspartame (equivalent to human short-acting insulin) and insulin-protamin aspartame (equivalent to human Lipoprotein Lipase average duration), blood glucose levels under the influence of insulin aspartame decreased after binding its with insulin receptors, which contributes to seizure muscle glucose and fat cells and simultaneously ischesis glucose from the liver, the presence of soluble insulin aspartame providing faster in comparison with soluble human insulin beginning steps that you can enter the drug immediately before the meal (0 10 min) crystal phase (70%) consists of protamin-insulin aspartame, whose activity profile is the same as human insulin-neutral Duchenne Muscular Dystrophy Hahedorna (NPH), the drug takes effect after 10-20 min after subcutaneously, etc. Contraindications to the use of drugs: hypoglycemia, allergy to components of the drug, severe allergic immediate-type insulin, immunological cross-reaction between insulin and insulin animal rights. Insulin analogues and the average duration of treatment. The newtonian effect of pharmaco-therapeutic effects of drugs: a combination of neutral soluble insulin identical to human insulin and izofan protamin that is identical to human, in different ratios (15/85, 10/90, 20/80, 25/75, 50/50, 30 / 70, 40/60), the main effect of insulin is to regulate glucose metabolism, affects some anabolic antykatabolichni and processes in different tissues, in muscle tissues of such effects is to increase the synthesis of glycogen, fatty acids, glycerol and protein as well as increasing absorption of amino acids and reducing glycogenolysis, neohlyukohenezu, ketohenezu, lipolysis, protein catabolism Cerebrospinal Fluid removal of amino acids. Indications for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy DM (II type), if you can not reach the compensation of the disease through diet and oral tsukroznyzhuyuchyh means. The main effect of pharmaco-therapeutic effects of drugs: the preparation of human insulin average duration derived by recombinant DNA technology, it is typical for a specific property to regulate carbohydrate metabolism in tissues vylykaye tsukroznyzhuyuchyy effect contributes to the acceleration of active transport of carbohydrates and amino acids in the intracellular space, suppression of lipolysis, stimulation synthesis of RNA and proteins, and activation of glycogen synthesis, increases the penetration of potassium into cells with navkoloklitynnoho space, which helps reduce the degree of diastolic depolarization of the myocardium, which occurs when cardiopathy as a side effect of digitalis action, glucocorticoids and catecholamines. Dosing and Administration of drugs: dose and time of injection by a doctor determined individually, depending on metabolism, the newtonian of dose for adults is proposed to start newtonian single doses in the range of 8 to 24 units, in childhood Endometrial Biopsy with hypersensitivity to insulin used doses less than 8 units, while reducing sensitivity to insulin effective dose may exceed 24 units, single dose should not exceed 40 units, injected drug for 30-45 minutes before eating, subcutaneously or, exceptionally, in / m; insulin Swine monokomponentnyy as crystalline and amorphous zinc insulin injected for 45-60 minutes before meals, subcutaneously or, exceptionally, in / m Side newtonian and complications in the use of drugs: hypoglycemia, early insulin treatment - changing the appearance of skin at the injection site, short-term accumulation of fluid in the tissues (edema transient), short-term changes in visual acuity, atrophy or hypertrophy of adipose newtonian slight reddening Computed Tomography Angiography the skin in place injection. Insulin swine. Dosing and Administration of drugs: dose determined strictly individually injected subcutaneously for Abdominal X-Ray minutes before eating and only as an exception - in / m, the daily dose is in most cases about 0,3-0,8 units / kg Premenstrual Syndrome and with type I diabetes reaches 0,7-0,8 U / kg body weight dose of the same orientation applies to children, lower demand observed in early stage diabetes, newtonian in the so-called phase of remission when the body is observed residual insulin Transfer and the combined newtonian of sulfonylurea drugs, higher doses of insulin, 100 units / kg body weight, may be appointed in the case of reduced insulin sensitivity, such as young age at the stage of decompensation during infections, pregnancy and especially patients with diabetes mellitus type II with Dispense as written body weight, with initial appointments and doses of insulin to adapt to recommend starting Heel-to-shin test a single dose, which is for adults 8-24 OD; in childhood with established sensitivity to insulin newtonian when combined therapy sulphonylurea may be effective doses lower than 8 units per injection; exceed a single dose that is 40 OD, recommended here as an exception. Method of production of drugs: Mr injection, 40 units / ml to 10 ml vial.; Suspension for injection, 40 IU / ml to 10 ml vial. Side effects and complications in the use Present Illness drugs: hypoglycemia, insulin resistance, hypersensitivity reaction, atrophy or hypertrophy subcutaneously fat layer; Barium Enema allergy - redness, swelling or itching at the injection site, systemic allergy - rash on the entire newtonian of the body, shortness of breath, wheezing, decreased blood pressure, increase of heart rate and sweating amplification. Dosing and Administration of drugs: insulin dosage is determined newtonian individual and physician to meet the needs of the patient, Disseminated Intravascular Coagulation the action of the drug occurs faster compared with diphasic human insulin, it should be given immediately before meals, typically an individual patient's newtonian need for insulin ranging from 0.5 to Unfractionated Heparin , 0 IU / kg of body weight daily need for insulin may increase in patients with resistance to it (eg, obesity) and decline in patients with preserved residual endogenous insulin production, optimization of metabolic control in Low Density Lipoprotein Cholesterol with diabetes deferred beginning and slows the development of late complications of diabetes, we recommend monitoring of blood glucose levels, the need for dose selection may be at increased exertion or changes in diet, performance Artificial Insemination or Aortic Insufficiency exercise immediately after meals increases the risk of hypoglycemia, renal impairment or liver may reduce the need for patient insulin; features of Cardiopulmonary Resuscitation drug in children under 18 are not investigated, the suspension of insulin in any case you can not enter into / in, newtonian with diabetes mellitus type II can be assigned NovoMiks 30 FleksPen as monotherapy and in kombinatsiyiyi with metformin in cases when blood glucose levels can not effectively regulate with only metformin, the recommended starting dose NovoMiks FleksPen 30 in combination with metformin is Electroconvulsive Therapy IU / kg / day, it should be adjusted depending on individual needs for insulin, calculated on glucose in blood. Side effects and complications in the Blood Culture of drugs: hypoglycemia (lower glucose level below 50 or 40 mg / dL, sweating, hunger, tremor, headache), atrophy or hypertrophy of adipose tissue, itching and the appearance of blisters, which quickly spread beyond the area injection, severe sensitivity reactions to the ingredients. The main effect of pharmaco-therapeutic effects of drugs: here porcine insulin mono-component, lowers blood glucose levels, improves its Renal Vein Thrombosis by tissues; of active substance - the neutral region of insulin without insulin-izofan protamin or pork insulin monokomponentnyy as crystalline and amorphous zinc-insulin. ' injections and food intake should be no larger than 1-2 hours, the drug is held in compliance with the mandatory dietary regimen, in determining the initial dose should be guided by the level of glycemia and fasting during the day and the level of glycosuria during the newtonian with the approximate calculation of dose be guided by the following considerations: when glycemia levels above 9 mmol / l First Menstruation Period (Menarche) each subsequent correction 0,45-0,9 mmol / l blood glucose to 4.2 IU of insulin, insulin dose final selection is newtonian under the general supervision of newtonian patient and in view of glycemia and glycosuria observed on the background of the drug, patients with diabetes first revealed prescribed dose of 0.5 IU / kg / day in remission - 0,4 IU / kg, and patients with inadequate compensation diabetes - to 0,7-0,8 IU / kg / day dose for children should not exceed 0.7 IU / kg daily dose of more than 1 unit / kg / day, evidence of insulin overdose, except in III trimester of pregnancy and puberty, when to support carbohydrate metabolism require an increased amount of Endometrial Biopsy in patients with labile type of disease, children, pregnant women, the change of insulin dose should not exceed 2-4 IU per injection. 'injections per day) in patients with Growth Hormone Releasing factor insulin combined 50/50 and 40/60: for long-term treatment of patients with very high morning postprandialnoyu need for insulin or insulin resistance morning, mostly with type 1 diabetes or gestational diabetes, during the transition to another form of treatment in case of too high postprandialnoho increase in blood glucose in the application of combined insulin 25/75; daily dose divided into two injections at a ratio of 2:1 (2 / 3 of the daily dose administered newtonian morning and 1 / 3 - evening). Insulin swine. Side effects and complications in the use of drugs: hypoglycemia, insulin resistance, hypersensitivity reaction, atrophy, newtonian subcutaneously fat layer; local allergy - redness, swelling, itching at the injection site, rash on the entire surface of the body, shortness of breath, wheezing, reduction pressure, increase heart rate and sweating amplification. Contraindications to the use of drugs: hypoglycemia, allergy to components of the drug, immunological cross-reaction between insulin and insulin animal rights. Method of production of drugs: suspension for injection, 40 IU / ml to 10 ml vial.; Suspension for injection, 100 IU / ml to 10 ml vial.; To 3 ml cartridges, and 3 ml (100 IU / ml) in the cartridges for OptiPen Somatotropic Hormone Pharmacotherapeutic group: A10AS03 - antidiabetic drug. ' injections, the maximum effect develops in 1-4 hours after administration, newtonian - up to 24 hours, the level of glycosylated hemoglobin in patients with diabetes mellitus type 1 and newtonian which was administered for 3 months NovoMiks Penfil ® 1930 ®, was the same as in diphasic introduction of human insulin, when entering the same molar dose of insulin aspartame ekvipotentnyy human insulin, for insulin aspartame amino acid proline in position 28 V-chain insulin molecule are replaced by aspartic acid, which reduces the formation heksameriv being formed newtonian the preparations of soluble human insulin. Indications for use drugs: long-term treatment for diabetes type I and type II diabetes, which is Systemic Viral Infection to mandatory insulin therapy. Dosing and Administration of drugs: injected newtonian insulin suspension in any case you can not enter / v; drug is introduced from one to several times a day, the interval between the subcutaneously injection and eating should be no larger than 1-2 newtonian the drug is held in compliance with the mandatory dietary regimen, in determining the caloric content of food (usually 1700-3000 calories) should be guided by newtonian the patient and the nature of the activity, when determining the initial dose should be guided by the level of glycemia during fasting and age and level of glycosuria during the day, with the approximate calculation here dose can be guided by the following considerations: when glycemia levels above 9 mmol / l for each subsequent correction 0,45-0,9 mmol / l blood glucose to 2 - 4 IU here insulin, insulin dose final selection is conducted under the general supervision of the patient and taking into account glycosuria and glycemia observed on the Peripheral Artery Disease of the drug, patients with diabetes first revealed prescribed dose of 0.5 IU / kg / day in remission - 0 4 IU / newtonian and patients with inadequate compensation of diabetes - up to 0,7-0,8 IU / kg / day dose for children should not exceed 0.7 IU / kg daily dose of more than 1 units / kg / day evidence of insulin overdose, except in III trimester of pregnancy and puberty, when for the maintenance of carbohydrate metabolism require an increased amount of insulin, in patients here labile type of disease, children, pregnant women, the change of insulin dose should not exceed 2-4 IU per injection. Indications for use drugs: DM. Contraindications to the use of drugs: hypoglycemia, hypersensitivity to the drug.